PENSTREP 20/25 INJ.

PENSTREP 20/25 INJ.

COMPOSITION

Contains per ml:

Procaine penicillin G 200 mg

Dihydrostreptomycin sulphate 250 mg

DESCRIPTION

Procaine penicillin G is a small-spectrum penicillin with bactericidal action

against mainly Gram-positive bacteria (like Streptococci, Staphylococci,

some Corynebacteria spp., Erysipelothrix rhusiopathiae, Clostridia spp.,

Bacillus anthracis) and Gram-negative cocci, Leptospira canicola,

Campylobacter foetus and Actinomyces bovis.

Dihydrostreptomycin, an aminoglycoside antibiotic, has bactericidal activity against mainly Gram-negative bacteria, like

E. coli, Proteus vulgaris, Brucella spp., Salmonella spp., Shighella spp., Klebsiella spp., Pasteurella spp. and some

Mycoplasmas. The combination acts additive and in some cases synergistic.

INDICATIONS

Penstrep 20/25 Inj. is effective against infections caused by micro-organisms susceptible to penicillin or

dihydrostreptomycin, like respiratory, uterine, and alimentary infections, metritis, mastitis, osteomyelitis, peritonitis,

septicaemia, cystitis, joint-ill and secondary bacterial infections in cattle, horses, pigs, foals, calves, sheep and goats.

CONTRA-INDICATIONS

Do not administer to animals hypersensitive to penicillins, aminoglycosides and/or procaine. Do not administer to

animals with renal dysfunctions, disturbances of auditory or vestibular organs. Do not use in small herbivores like

rabbits, chinchillas and guinea pigs, not for prolonged use in pregnant animals because of the risk of toxicity to the

foetus.

SIDE-EFFECTS

Prolonged administration of high doses may result in renal, vestibular and/or auditory dysfunctions. Sometimes

hypersensitivity reactions may occur.

INCOMPATIBILITY WITH OTHER DRUGS OR SUBSTANCES

Penstrep 20/25 Inj. is incompatible with fast-acting bacteristatic antimicrobial drugs (e.g. tetracyclines,

chloramphenicol, erythromycin, lincomycin) and with anaesthetics or other neuromuscular blocking agents (because of

respiratory depression and apnoea).

DOSAGE AND ADMINISTRATION

For intramuscular injection. Shake well before use.

General dose : 1 ml per 25 kg bodyweight daily, during 3 – 4 days.

In severe cases this dose may be doubled.

WITHDRAWAL PERIOD

Meat : 10 days

Milk : 3 days

STORAGE

Store in a dry, dark place between 8°C and 15°C.

Keep medicine away from children.

PACKING

100 ml multidose vial (48 vials per box).

Producer: Kepro B.V. (Netherlands)