Glucadex

Glucadex 2 mg/mL solution for injection for horses, cattle, goats, pigs, dogs and cats
dexamethasone (as sodium phosphate).
STATEMENT OF THE ACTIVE SUBSTANCE AND OTHER INGREDIENTS
1 mL contains:
Active substance:
Dexamethasone 2,0 mg
(as dexamethasone sodium phosphate 2,63 mg)
Excipients:
Benzyl alcohol (E1519) 15,6 mg
Solution for injection.
Clear, colourless aqueous solution.

INDICATIONS
Horses, cattle, goats, pigs, dogs and cats:
Treatment of inflammation and allergic reactions.
Horses: Treatment of arthritis, bursitis or tenosynovitis.
Cattle: Treatment of primary ketosis (Acetonemia).
Induction of parturition.
Goats: Treatment of primary ketosis (Acetonemia).

CONTRAINDICATIONS
Except in emergency situations, do not use in animals suffering from diabetes mellitus,
renal insufficiency, cardiac insufficiency, hyperadrenocorticism or osteoporosis.
Do not use in viral infections during the viraemic stage or in cases of systemic mycotic
infections.
Do not use in animals suffering from gastrointestinal or corneal ulcers, or demodicosis.
Do not administer intra-articularly where there is evidence of fractures, bacterial joint
infections and aseptic bone necrosis.
Do not use in cases of hypersensitivity to the active substance, to corticosteroids and to any
other ingredient of the product.
See also the on section use during pregnancy and lactation.

DOSAGE FOR EACH SPECIES, ROUTES AND METHOD OF ADMINISTRATION
Horses: Intravenous, intramuscular, intraarticular and peri-articular use.
Dogs and cats: Intravenous, intramuscular and subcutaneous use.
Cattle, goats and pigs: Intravenous and intramuscular use
For the treatment of inflammatory or allergic conditions the following average doses are
advised. However the actual dose used should be determined by the severity of the signs
and the length of time for which they have been present.

Species Dosage
Horses, cattle, goats, pigs 0,06 mg of dexamethasone/kg bw
(1,5 mL of product/50 kg bw)
Dog, cat 0,1 mg of dexamethasone/ kg bw
(0,5 mL of product/10 kg bw)
For the treatment of primary ketosis in cattle a dose of 0,02-0,04 mg of dexamethasone/kg
bw (cattle: 5-10 mL of product per 500 kg bw; goats: 0,65-1,3 mL of product per 65 kg bw)
given by single intramuscular injection is advocated dependent on the size of the animal
and the duration of the signs. Higher doses (i.e. 0,04 mg/kg) will be required if the signs
have been present for some time or if relapsed animals are being treated.
For the induction of parturition in cattle – to avoid foetal oversize and mammary oedema.
A single intramuscular injection of 0,04 mg of dexamethasone/kg bw (corresponding to 10
mL of product for a cow weighing 500 kg) after day 260 of pregnancy.
Parturition will normally occur within 48-72 hours.
For the treatment of arthritis, bursitis or tenosynovitis by intra-articular or peri-articular
injection in the horse.
Dose 1 – 5 mL of product per treatment.
These quantities are not specific and are quoted purely as a guide. Injections into joint
spaces or bursae should be preceded by the removal of an equivalent volume of synovial
fluid. Strict asepsis is essential.

WITHDRAWAL PERIODS
Cattle and goats : Meat and offal : 8 days
Milk : 72 hours
Pigs : Meat and offal : 2 days following intramuscular administration
Meat and offal : 6 days following intravenous administration
Horses : Meat and offal : 8 days
Not authorized for use in horses producing milk for human consumption.

SPECIAL STORAGE PRECAUTIONS
Keep out of the sight and reach of children.
Keep the vial in the outer carton in order to protect from light.
Do not use this veterinary medicinal product after the expiry date which is stated on the
carton and label after EXP. The expiry date refers to the last day of that month.
Shelf life after first opening the container: 28 days.