{"id":9226,"date":"2021-10-20T15:54:56","date_gmt":"2021-10-20T11:54:56","guid":{"rendered":"https:\/\/megavet.ge\/product\/sipmarica-sarolaner\/"},"modified":"2022-10-04T11:01:27","modified_gmt":"2022-10-04T07:01:27","slug":"sipmarica-sarolaner","status":"publish","type":"product","link":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/","title":{"rendered":"Sipmarica (Sarolaner)"},"content":{"rendered":"<article class=\"two-col-image-tile clearfix no-img \">\n<div class=\"authorable\">\n<div class=\"home-bottom\">\n<div class=\"home-left\">\n<p>Simparica\u00a0(Sarolaner) Acts\u00a0Fast<\/p>\n<ul>\n<li>Starts killing ticks within 8\u00a0hours<\/li>\n<li>Starts killing fleas within 3\u00a0hours<\/li>\n<li>35 days of protection without losing effectiveness at the end of the\u00a0month<\/li>\n<li>Kills 5 species of\u00a0ticks<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"authorable\">\n<p>Studies show Simparica starts killing ticks in 8 hours and is \u226596.9% effective for 35 days against weekly reinfestations of <i>Ixodes scapularis<\/i>,\u00a0<i>Amblyomma\u00a0americanum<\/i>,\u00a0<i>Amblyomma\u00a0maculatum<\/i>,\u00a0<i>Dermacentor variabilis<\/i>, and\u00a0<i>Rhipicephalus\u00a0sanguineus<\/i>.<sup>1,2<\/sup><\/p>\n<p><strong>Description<\/strong><\/p>\n<p>SIMPARICA is a flavored, chewable tablet for administration to dogs over 6 months of age according to their weight. Each tablet is formulated to provide a minimum sarolaner dosage of 0.91 mg\/lb (2 mg\/kg) body weight.<\/p>\n<p>Sarolaner is a member of the isoxazoline class of parasiticides and the chemical name is 1 &#8211; (5\u2019 &#8211; ((5S) &#8211; 5 &#8211; (3,5 &#8211; Dichloro &#8211; 4 &#8211; fluorophenyl) &#8211; 5 &#8211; (trifluoromethyl) &#8211; 4,5 &#8211; dihydroisoxazol &#8211; 3 &#8211; yl) &#8211; 3\u2019 &#8211; H &#8211; spiro(azetidine &#8211; 3,1\u2019 &#8211; (2)benzofuran) &#8211; 1 &#8211; yl) &#8211; 2 &#8211; (methylsulfonyl)ethanone. SIMPARICA contains the S-enantiomer of sarolaner.<\/p>\n<p><strong>Simparica (sarolaner) Chewables Indications<\/strong><\/p>\n<p>SIMPARICA kills adult fleas, and is indicated for the treatment and prevention of flea infestations\u00a0<i>(Ctenocephalides felis)<\/i>, and the treatment and control of tick infestations [<i>Amblyomma americanum<\/i>\u00a0(lone star tick),\u00a0<i>Amblyomma maculatum<\/i>\u00a0(Gulf Coast tick),\u00a0<i>Dermacentor variabilis<\/i>\u00a0(American dog tick),\u00a0<i>Ixodes scapularis<\/i>\u00a0(black-legged tick), and\u00a0<i>Rhipicephalus sanguineus<\/i>\u00a0(brown dog tick)] for one month in dogs 6 months of age or older and weighing 2.8 pounds or greater.<\/p>\n<p>SIMPARICA is indicated for the prevention of\u00a0<i>Borrelia burgdorferi<\/i>\u00a0infections as a direct result of killing\u00a0<i>Ixodes scapularis<\/i>\u00a0vector ticks.<\/p>\n<p><strong>Dosage and Administration<\/strong><\/p>\n<p>SIMPARICA is given orally once a month at the recommended minimum dosage of 0.91 mg\/lb (2 mg\/kg).<\/p>\n<p>Dosage Schedule:<\/p>\n<div class=\"responsive-table-wrap\">\n<table>\n<tbody>\n<tr>\n<td colspan=\"1\" rowspan=\"1\"><b>Body Weight<\/b><\/td>\n<td colspan=\"1\" rowspan=\"1\"><b>SAROLANER per Tablet (mg)<\/b><\/td>\n<td colspan=\"1\" rowspan=\"1\"><b>Number of Tablets Administered<\/b><\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">2.8 to 5.5 lbs<\/td>\n<td colspan=\"1\" rowspan=\"1\">5<\/td>\n<td colspan=\"1\" rowspan=\"1\">One<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">5.6 to 11.0 lbs<\/td>\n<td colspan=\"1\" rowspan=\"1\">10<\/td>\n<td colspan=\"1\" rowspan=\"1\">One<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">11.1 to 22.0 lbs<\/td>\n<td colspan=\"1\" rowspan=\"1\">20<\/td>\n<td colspan=\"1\" rowspan=\"1\">One<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">22.1 to 44.0 lbs<\/td>\n<td colspan=\"1\" rowspan=\"1\">40<\/td>\n<td colspan=\"1\" rowspan=\"1\">One<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">44.1 to 88.0 lbs<\/td>\n<td colspan=\"1\" rowspan=\"1\">80<\/td>\n<td colspan=\"1\" rowspan=\"1\">One<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">88.1 to 132.0 lbs<\/td>\n<td colspan=\"1\" rowspan=\"1\">120<\/td>\n<td colspan=\"1\" rowspan=\"1\">One<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">&gt;132.1 lbs<\/td>\n<td colspan=\"2\" rowspan=\"1\">Administer the appropriate combination of tablets<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div id=\"display-ad-injection-2\" class=\"display-ad display-ad-injection display-ad-lazy display-ad-prebid display-ad-728 display-ad-728x90\" data-google-query-id=\"COq1nLmr5fMCFWHwuwgdGR4KVg\">\n<div id=\"google_ads_iframe_\/7146\/vet_5__container__\"><iframe id=\"google_ads_iframe_\/7146\/vet_5\" title=\"3rd party ad content\" name=\"google_ads_iframe_\/7146\/vet_5\" width=\"728\" height=\"90\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" sandbox=\"allow-forms allow-popups allow-popups-to-escape-sandbox allow-same-origin allow-scripts allow-top-navigation-by-user-activation\" data-google-container-id=\"6\" data-load-complete=\"true\" data-mce-fragment=\"1\"><\/iframe><\/div>\n<\/div>\n<p>SIMPARICA can be offered by hand, in the food, or administered like other tablet medications.<\/p>\n<p>Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If a dose is missed, administer SIMPARICA and resume a monthly dosing schedule.<\/p>\n<p>SIMPARICA should be administered at monthly intervals.<\/p>\n<p><i>Flea Treatment and Prevention:<\/i><\/p>\n<p>Treatment with SIMPARICA may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with SIMPARICA can continue the entire year without interruption.<\/p>\n<p>To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with an approved flea control product.<\/p>\n<p><i>Tick Treatment and Control:<\/i><\/p>\n<p><strong>Contraindications<\/strong><\/p>\n<p>There are no known contraindications for the use of SIMPARICA.<\/p>\n<p><strong>Warnings<\/strong><\/p>\n<p>Not for use in humans. Keep this and all drugs out of reach of children. For use in dogs only. Do not use SIMPARICA in cats.<\/p>\n<p>Keep SIMPARICA in a secure location out of reach of dogs, cats and other animals to prevent accidental ingestion or overdose.<\/p>\n<p><strong>Precautions<\/strong><\/p>\n<p>Sarolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.<\/p>\n<p>The safe use of SIMPARICA has not been evaluated in breeding, pregnant, or lactating dogs.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Simparica\u00a0(Sarolaner) Acts\u00a0Fast Starts killing ticks within 8\u00a0hours Starts killing fleas <a href=\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/\"> &#8230;<\/a><\/p>\n","protected":false},"featured_media":9157,"template":"","meta":[],"product_brand":[],"product_cat":[148],"product_tag":[],"food-animal":[],"manufacturers":[415],"food-manufacturer":[],"shape":[347],"animals":[204,198],"class_list":{"0":"post-9226","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-antiparazit","7":"manufacturers-zoetis","8":"shape-tablet-en","9":"animals-all-animals","10":"animals-dogs","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sipmarica (Sarolaner) &#8226; Megavet<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sipmarica (Sarolaner) &#8226; Megavet\" \/>\n<meta property=\"og:description\" content=\"Simparica\u00a0(Sarolaner) Acts\u00a0Fast Starts killing ticks within 8\u00a0hours Starts killing fleas ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/\" \/>\n<meta property=\"og:site_name\" content=\"Megavet\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Megavet-572105553316486\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-04T07:01:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"1000\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/\",\"url\":\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/\",\"name\":\"Sipmarica (Sarolaner) &#8226; Megavet\",\"isPartOf\":{\"@id\":\"https:\/\/megavet.ge\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg\",\"datePublished\":\"2021-10-20T11:54:56+00:00\",\"dateModified\":\"2022-10-04T07:01:27+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#primaryimage\",\"url\":\"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg\",\"contentUrl\":\"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg\",\"width\":1000,\"height\":1000},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u10db\u10d7\u10d0\u10d5\u10d0\u10e0\u10d8\",\"item\":\"https:\/\/megavet.ge\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Products\",\"item\":\"https:\/\/megavet.ge\/en\/products\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Antiparasitic Products\",\"item\":\"https:\/\/megavet.ge\/en\/product-category\/antiparazit\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Sipmarica (Sarolaner)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/megavet.ge\/#website\",\"url\":\"https:\/\/megavet.ge\/\",\"name\":\"Megavet\",\"description\":\"\u10e7\u10d5\u10d4\u10da\u10d0\u10e4\u10d4\u10e0\u10d8 \u10ea\u10ee\u10dd\u10d5\u10d4\u10da\u10d7\u10d0 \u10ef\u10d0\u10dc\u10db\u10e0\u10d7\u10d4\u10da\u10dd\u10d1\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1\",\"publisher\":{\"@id\":\"https:\/\/megavet.ge\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/megavet.ge\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/megavet.ge\/#organization\",\"name\":\"Megavet | \u10db\u10d4\u10d2\u10d0\u10d5\u10d4\u10e2\u10d8\",\"url\":\"https:\/\/megavet.ge\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/megavet.ge\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/02\/logo-1.png\",\"contentUrl\":\"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/02\/logo-1.png\",\"width\":159,\"height\":118,\"caption\":\"Megavet | \u10db\u10d4\u10d2\u10d0\u10d5\u10d4\u10e2\u10d8\"},\"image\":{\"@id\":\"https:\/\/megavet.ge\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/Megavet-572105553316486\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sipmarica (Sarolaner) &#8226; Megavet","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/","og_locale":"en_US","og_type":"article","og_title":"Sipmarica (Sarolaner) &#8226; Megavet","og_description":"Simparica\u00a0(Sarolaner) Acts\u00a0Fast Starts killing ticks within 8\u00a0hours Starts killing fleas ...","og_url":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/","og_site_name":"Megavet","article_publisher":"https:\/\/www.facebook.com\/Megavet-572105553316486","article_modified_time":"2022-10-04T07:01:27+00:00","og_image":[{"width":1000,"height":1000,"url":"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/","url":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/","name":"Sipmarica (Sarolaner) &#8226; Megavet","isPartOf":{"@id":"https:\/\/megavet.ge\/#website"},"primaryImageOfPage":{"@id":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#primaryimage"},"image":{"@id":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#primaryimage"},"thumbnailUrl":"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg","datePublished":"2021-10-20T11:54:56+00:00","dateModified":"2022-10-04T07:01:27+00:00","breadcrumb":{"@id":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#primaryimage","url":"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg","contentUrl":"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/10\/SIMPAR.jpg","width":1000,"height":1000},{"@type":"BreadcrumbList","@id":"https:\/\/megavet.ge\/en\/product\/sipmarica-sarolaner\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u10db\u10d7\u10d0\u10d5\u10d0\u10e0\u10d8","item":"https:\/\/megavet.ge\/en\/"},{"@type":"ListItem","position":2,"name":"Products","item":"https:\/\/megavet.ge\/en\/products\/"},{"@type":"ListItem","position":3,"name":"Antiparasitic Products","item":"https:\/\/megavet.ge\/en\/product-category\/antiparazit\/"},{"@type":"ListItem","position":4,"name":"Sipmarica (Sarolaner)"}]},{"@type":"WebSite","@id":"https:\/\/megavet.ge\/#website","url":"https:\/\/megavet.ge\/","name":"Megavet","description":"\u10e7\u10d5\u10d4\u10da\u10d0\u10e4\u10d4\u10e0\u10d8 \u10ea\u10ee\u10dd\u10d5\u10d4\u10da\u10d7\u10d0 \u10ef\u10d0\u10dc\u10db\u10e0\u10d7\u10d4\u10da\u10dd\u10d1\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1","publisher":{"@id":"https:\/\/megavet.ge\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/megavet.ge\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/megavet.ge\/#organization","name":"Megavet | \u10db\u10d4\u10d2\u10d0\u10d5\u10d4\u10e2\u10d8","url":"https:\/\/megavet.ge\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/megavet.ge\/#\/schema\/logo\/image\/","url":"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/02\/logo-1.png","contentUrl":"https:\/\/megavet.ge\/wp-content\/uploads\/2021\/02\/logo-1.png","width":159,"height":118,"caption":"Megavet | \u10db\u10d4\u10d2\u10d0\u10d5\u10d4\u10e2\u10d8"},"image":{"@id":"https:\/\/megavet.ge\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/Megavet-572105553316486"]}]}},"_links":{"self":[{"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/product\/9226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/media\/9157"}],"wp:attachment":[{"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/media?parent=9226"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/product_brand?post=9226"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/product_cat?post=9226"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/product_tag?post=9226"},{"taxonomy":"food-animal","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/food-animal?post=9226"},{"taxonomy":"manufacturers","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/manufacturers?post=9226"},{"taxonomy":"food-manufacturer","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/food-manufacturer?post=9226"},{"taxonomy":"shape","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/shape?post=9226"},{"taxonomy":"animals","embeddable":true,"href":"https:\/\/megavet.ge\/en\/wp-json\/wp\/v2\/animals?post=9226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}